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Hemin

产品编号:3095779
规格:BioXtra, from Porcine, ≥97.0% (HPLC)
CAS NO:16009-13-5
包装规格:1G,5G,25G
产品类别:
品牌:Sigma
产品价格
产品编号包装单位价格(元)国内现货国外库存购物车
30957791G657
30957795G2300
309577925G7600
产品别名

16009-13-5

Hemin

Chloro(protoporphyrinato)iron(III)

Chlorohemin

Chloroprotoporphyrin IX iron(III)

Ferriprotoporphyrin IX chloride

Hemin(chloride)

结构式
基本信息
经验分子式(希尔表示法)
C34H32ClFeN4O4
分子量
651.94
Beilstein Registry Number【贝尔斯坦登记号】
5229914
EINECS 编号【欧洲现有商业化学物质名录编号】
240-140-1
MDL number【MDL编号(化学反应和变化识别号)】
MFCD00010726
Frequently Asked Questions【常见问题】
Frequently Asked Questions are available for this Product.
Application【应用】
Hemin is used for the following applications:
· To study bacterial strains and growth conditions
· Used in short-term colony assays (the culture medium consists of hemin along with other components)
· Cell transfections
It may be used in β-hematin formation assay for analyzing the inhibitory activity of MMV (Medicines for Malaria Venture) Malaria Box compounds against the formation of β-hematin.
Biochem/physiol Actions【生物化学/生理学作用】
Hemin, the oxidized version of heme, is an iron-containing prosthetic group for a diverse group of proteins. Free heme, which can be released from hemoglobin following hemolysis, is pro-inflammatory and contributes to iron-derived reactive oxygen species. Free hemin levels may be upregulated in various pathological conditions and can contribute to various inflammatory conditions including vascular disorders, renal failure, and immune-mediated disorders.
Hemin may be used to study the expression and represson of heme oxygenase 1 (HO-1) as well as the activity of HO-1. Hematin is the "X factor" required to grown Haemophilus influenzae.
产品性质
biological source【生物源】
from Porcine
product line【产品线】
BioXtra
Assay【含量】
≥97.0% (HPLC)
storage temp.【存储温度】
2-8℃
安全信息
个人防护装备
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR【欧洲内陆运输危险品】
NONH for all modes of transport
WGK德国【德国水污染分类】
3
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